Resource Type

Journal Article 38

Conference Videos 1

Year

2023 8

2022 7

2021 3

2020 3

2019 3

2018 4

2017 4

2013 3

2011 1

open ︾

Keywords

Gut microbiota 14

gut microbiota 6

Probiotics 2

acute rejection 2

gut 2

Bifidobacterium longum 1

Devosia 1

Eubacterium 1

Lactobacillus plantarum 1

Phaeodactylum tricornutum Bohlin 1

ADT-OH 1

Acute liver failure 1

Adaptive evolution 1

Akkermansia muciniphila 1

Allergic diseases 1

Antibiotic 1

Aquaculture 1

Aryl hydrocarbon receptor 1

Atherosclerosis 1

open ︾

Search scope:

排序： Display mode:

Nutritional and Metabolic Consequences of Feeding High-Fiber Diets to Swine: A Review

Atta K. Agyekum, C. Martin Nyachoti

Engineering 2017, Volume 3, Issue 5,   Pages 716-725 doi: 10.1016/J.ENG.2017.03.010

Abstract: On the other hand, dietary fiber is increasingly used as a means of promoting pig gut health and gestatingIn this review, dietary fiber and its effects on pig nutrition, gut physiology, and sow welfare are discussed

Keywords： Gut physiology     High-fiber diets     Nutrient utilization     Pigs     Sow welfare    

HTML PDF Collect

Hormesis-like growth and photosynthetic physiology of marine diatom Bohlin exposed to polystyrene microplastics

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 1,   Pages 2-2 doi: 10.1007/s11783-021-1436-0

Abstract:

• Polystyrene microplastic caused hormesis-like effects in Phaeodactylum tricornutum.

Keywords： Microplastics     Marine microalgae     Phaeodactylum tricornutum Bohlin     Growth     Photosynthetic pigments     Chlorophyll fluorescence parameters    

HTML PDF Collect

Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology

Baicheng HUANG, Kegong TIAN

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2,   Pages 218-226 doi: 10.15302/J-FASE-2020324

Abstract:

Emergent coronaviruses (CoVs) such as SARS-CoV and MERS-CoV have posed great threats to public health worldwide over the past two decades. Currently, the emergence of SARS-CoV-2 as a pandemic causes greater public health concern. CoV diversity is due to the large size and replication mechanisms of the genomes together with having bats as their optimum natural hosts. The ecological behavior and unique immune characteristics of bats are optimal for the homologous recombination of CoVs. The relationship of spatial structural characteristics of the spike protein, a protein that is critical for recognition by host receptors, in different CoVs may provide evidence in explaining the coevolution of CoVs and their hosts. This information may help to enhance our understanding of CoV evolution and thus provide part of the basis of preparations for any future outbreaks.

Keywords： bat     coronavirus     evolution     host receptor     spike protein     transmission    

HTML PDF Collect

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract: Importantly, the resulting alteration of gut microbiota aggravates graft dysfunctions during the processThis article reviews the research progress for gut microbial alterations and liver transplantation.Especially, this work also evaluates research on the management of gut microbial alteration and the predictionIn addition, we propose possible directions for research on gut microbial alteration during liver transplantation

Keywords： gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

HTML PDF Collect

Integrated analysis of gut microbiome and host immune responses in COVID-19

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 263-275 doi: 10.1007/s11684-022-0921-6

Abstract: Emerging evidence indicates that the gut microbiome contributes to the host immune response to infectiousHere, to explore the role of the gut microbiome in the host immune responses in COVID-19, we conductedWe found that the diversity of the gut microbiome was reduced in severe/critical COVID-19 cases comparedWe identified the abundance of some gut microbes altered post-SARS-CoV-2 infection and related to diseasea correlation map between clinical features of COVID-19 and 16 severity-related gut microbe, including

Keywords： COVID-19     SARS-COV-2     gut microbiome     immune response    

HTML PDF Collect

Mechanistic and therapeutic advances in non-alcoholic fatty liver disease by targeting the gut microbiota

Ruiting Han, Junli Ma, Houkai Li

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 645-657 doi: 10.1007/s11684-018-0645-9

Abstract: disease because of the intricate role of gut microbiota in maintaining human health and disease formationMoreover, gut microbiota is even regarded as a “metabolic organ” that play complementary roles to thatAs a result, gut microbiota have been emerging as a novel therapeutic target for NAFLD by manipulatingIn this review, we summarized the most recent advances in gut microbiota-mediated mechanisms, as wellas gut microbiota-targeted therapies on NAFLD.

Keywords： gut microbiota     NAFLD     obesity     insulin resistance     bile acids     probiotic    

HTML PDF Collect

Calorie restriction and its impact on gut microbial composition and global metabolism

Xiaojiao Zheng, Shouli Wang, Wei Jia

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 634-644 doi: 10.1007/s11684-018-0670-8

Abstract: In the present review, we focus on the general effect of CR on gut microbiota composition and globalAnalyses of the gut microbial and host metabolisms revealed that most host microbial co-metabolites wereThe observed phenotypes and the further verification of the direct link between gut microbiota and metabolomeThus, improved gut microbiota composition and metabolome are potential biomarkers for determining the

Keywords： caloric restriction     gut microbiota     metabolome    

HTML PDF Collect

ADT-OH improves intestinal barrier function and remodels the gut microbiota in DSS-induced colitis

Frontiers of Medicine   Pages 972-992 doi: 10.1007/s11684-023-0990-1

Abstract: Owing to the increasing incidence and prevalence of inflammatory bowel disease (IBD) worldwide, effective and safe treatments for IBD are urgently needed. Hydrogen sulfide (H2S) is an endogenous gasotransmitter and plays an important role in inflammation. To date, H2S-releasing agents are viewed as potential anti-inflammatory drugs. The slow-releasing H2S donor 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione (ADT-OH), known as a potent therapeutic with chemopreventive and cytoprotective properties, has received attention recently. Here, we reported its anti-inflammatory effects on dextran sodium sulfate (DSS)-induced acute (7 days) and chronic (30 days) colitis. We found that ADT-OH effectively reduced the DSS-colitis clinical score and reversed the inflammation-induced shortening of colon length. Moreover, ADT-OH reduced intestinal inflammation by suppressing the nuclear factor kappa-B pathway. In vivo and in vitro results showed that ADT-OH decreased intestinal permeability by increasing the expression of zonula occludens-1 and occludin and blocking increases in myosin II regulatory light chain phosphorylation and epithelial myosin light chain kinase protein expression levels. In addition, ADT-OH restored intestinal microbiota dysbiosis characterized by the significantly increased abundance of Muribaculaceae and Alistipes and markedly decreased abundance of Helicobacter, Mucispirillum, Parasutterella, and Desulfovibrio. Transplanting ADT-OH-modulated microbiota can alleviate DSS-induced colitis and negatively regulate the expression of local and systemic proinflammatory cytokines. Collectively, ADT-OH is safe without any short-term (5 days) or long-term (30 days) toxicological adverse effects and can be used as an alternative therapeutic agent for IBD treatment.

Keywords： inflammatory bowel disease     ADT-OH     intestinal permeability     gut microbiota    

HTML PDF Collect

From gut changes to type 2 diabetes remission after gastric bypass surgeries

Bing Li, Xinrong Zhou, Jiarui Wu, Huarong Zhou

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 191-200 doi: 10.1007/s11684-013-0258-2

Abstract:

Increasing evidence suggests that the gut may influence the host’s metabolism and ultimatelyWe review the evidence on the relationship between the gut and T2DM remission after gastric bypass surgery, and discuss the potential mechanisms underlying the above relationship: gut anatomical rearrangement, microbial composition changes, altered gut cells, and gut hormone modulation.

Keywords： gastric bypass     T2DM     gut    

HTML PDF Collect

Effect of a new antitranspirant on the physiology and water use efficiency of soybean under different

Shasha JI, Ling TONG, Fusheng LI, Hongna LU, Sien LI, Taisheng DU, Youjie WU

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 2,   Pages 155-164 doi: 10.15302/J-FASE-2017148

Abstract: Antitranspirants are exogenous substances applied to leaves to reduce luxury transpiration by regulating stomatal conductance to increase water use efficiency (WUE). A cheap and environmentally-friendly antitranspirant, FZ, was newly developed, extracted mainly from . Its effects on soybean water use were investigated in a field experiment using the locally-used irrigation rate and a low irrigation rate (The lower and upper limit of irrigation is 40%–70% of field capacity). Foliar application of FZ and measurement of leaf physiological characteristics, final biomass, seed yield and water use efficiency were carried out during the pod bearing and pod filling stages of drip-irrigated soybean with film-mulching. Under the low irrigation rate, leaf stomatal conductance (g ) and transpiration rate (Tr) decreased significantly by 7 d after spraying, but photosynthesis (Pn) and instantaneous water use efficiency (WUE ) were not significantly affec ted. The stomatal frequency, stomatal aperture, g , Tr and Pn decreased by 1 d after spraying, without significantly increasing WUE . However, applying FZ during the pod bearing and pod filling stages did not significantly affect the final biomass, water consumption, seed yield and WUE of soybean. Under the locally-used irrigation rate, applying FZ increased the activities of superoxide dismutase and peroxidase in the leaves by 38% and 33%, respectively, but did not significantly affect g , Tr, Pn, stomatal aperture and stomatal frequency. Applying FZ three times during pod bearing and pod filling stages enhanced seed yield and WUE by 24% and 21%, respectively, but did not significantly affect the final biomass and water consumption. Therefore, seed yield and WUE of soybean were significantly increased by foliar application of FZ during the pod bearing and pod filling stages under the locally-used irrigation rate in arid region, but applying FZ did not have a positive effect on water use efficiency of soybean under a low irrigation rate.

Keywords： antitranspirant     soybean     water deficit     leaf gas exchange     enzymes activities     water consumption     seed yield    

HTML PDF Collect

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 25-30 doi: 10.1007/s11684-013-0244-8

Abstract:

Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor family. It actually functions as endocrine hormones but does not regulate cell growth and differentiation. It is demonstrated that FGF21 acts on multiple tissue to coordinate carbohydrate and lipid metabolism, including enhancing insulin sensitivity, decreasing triglyceride concentrations, causing weight loss, ameliorating obesity-associated hyperglycemia and hyperlipidemia. Moreover, FGF21 also plays important roles in some physiological processes, such as fasting and feeding, growth hormone axis and thermogenic function of brown adipose tissue. Clinical relevance of FGF21 in humans is still unclear, and the basis and consequences of increased FGF21 in metabolic disease remain to be determined. Both the pharmacological actions and physiological roles make FGF21 attractive drug candidates for treating metabolic disease, but some questions remain to be answered. This article concentrates on recent advances in our understanding of FGF21.

Keywords： FGF21     metabolism     pharmacology     physiology     clinical relevance    

HTML PDF Collect

Pien Tze Huang Protects Against Non-Alcoholic Steatohepatitis by Modulating the Gut Microbiota and Metabolites

Xianyi Zeng,Xiang Zhang,Hao Su,Hongyan Gou,Harry Cheuk-Hay Lau,Xiaoxu Hu,Ziheng Huang,Yan Li,Jun Yu,

Engineering doi: 10.1016/j.eng.2022.10.010

Abstract: Through the metagenomic sequencing of stool samples, we found that PTH administration restored the gutIn addition, PTH restored the gut barrier function in mice with steatohepatitis, as evidenced by reducedWe further confirmed that an intact gut microbiota is necessary for PTH to exhibit anti-steatohepatitisIn conclusion, PTH protects against steatohepatitis development by modulating the gut microbiota and

Keywords： Pien Tze Huang     Non-alcoholic steatohepatitis     Gut barrier function     Gut microbiota    

HTML PDF Collect

Biodegradation of waste refrigerator polyurethane by mealworms

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1638-8

Abstract:

● Waste refrigerator polyurethane (WRPU) was ingested and biodegraded by mealworms.

Keywords： Waste refrigerator polyurethane     Mealworms     Biodegradation     Carbon balance     Gut microorganism    

HTML PDF Collect

Modulation of Gut Microbiota in Pathological States

Yulan Wang, Baohong Wang, Junfang Wu, Xiangyang Jiang, Huiru Tang, Ole H. Nielsen

Engineering 2017, Volume 3, Issue 1,   Pages 83-89 doi: 10.1016/J.ENG.2017.01.013

Abstract: Our gut microbiota evolves with us and plays a pivotal role in human health and disease.recent years, the microbiota has gained increasing attention due to its impact on host metabolism, physiologyThe gut microbiota may be linked to malignancies such as gastric cancer and colorectal cancer., the aim of this review is to provide the reader with an updated overview of the importance of the gutThe concept of altering the gut community by microbial intervention in an effort to improve health is

Keywords： Gut microbes     Diseases     Microbial modulation    

HTML PDF Collect

Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 239-248 doi: 10.1007/s11684-018-0617-0

Abstract:

The gut microbiota is mainly composed of a diverse population of commensal bacterial species and playsThe influence of the gut microbiota on solid organ transplantation has recently been recognized.bowel transplantation (SBT) is closely associated with the alterations in microbial patterns in the gutFurthermore, we explored the potential of the gut microbiota as a microbial marker and/or therapeuticGiven that current research on the gut microbiota has become increasingly sophisticated and comprehensive

Keywords： gut microbiota     small bowel transplantation     acute rejection     chronic rejection     mucosal immunity     biomarker    

HTML PDF Collect

Title Author Date Type Operation

Nutritional and Metabolic Consequences of Feeding High-Fiber Diets to Swine: A Review

Atta K. Agyekum, C. Martin Nyachoti

Journal Article

Hormesis-like growth and photosynthetic physiology of marine diatom Bohlin exposed to polystyrene microplastics

Journal Article

Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology

Baicheng HUANG, Kegong TIAN

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article

Integrated analysis of gut microbiome and host immune responses in COVID-19

Journal Article

Mechanistic and therapeutic advances in non-alcoholic fatty liver disease by targeting the gut microbiota

Ruiting Han, Junli Ma, Houkai Li

Journal Article

Calorie restriction and its impact on gut microbial composition and global metabolism

Xiaojiao Zheng, Shouli Wang, Wei Jia

Journal Article

ADT-OH improves intestinal barrier function and remodels the gut microbiota in DSS-induced colitis

Journal Article

From gut changes to type 2 diabetes remission after gastric bypass surgeries

Bing Li, Xinrong Zhou, Jiarui Wu, Huarong Zhou

Journal Article

Effect of a new antitranspirant on the physiology and water use efficiency of soybean under different

Shasha JI, Ling TONG, Fusheng LI, Hongna LU, Sien LI, Taisheng DU, Youjie WU

Journal Article

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Journal Article

Pien Tze Huang Protects Against Non-Alcoholic Steatohepatitis by Modulating the Gut Microbiota and Metabolites

Xianyi Zeng,Xiang Zhang,Hao Su,Hongyan Gou,Harry Cheuk-Hay Lau,Xiaoxu Hu,Ziheng Huang,Yan Li,Jun Yu,

Journal Article

Biodegradation of waste refrigerator polyurethane by mealworms

Journal Article

Modulation of Gut Microbiota in Pathological States

Yulan Wang, Baohong Wang, Junfang Wu, Xiangyang Jiang, Huiru Tang, Ole H. Nielsen

Journal Article

Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Journal Article